C

Cholangiocarcinoma

Also known as bile duct cancer. The bile duct is a tube through which bile, a fluid made by the liver, passes from the liver to the gallbladder and small intestine.

CNS

Central nervous system, which includes the brain and spinal cord.

Colorectal cancer

Cancer that develops in the colon, which is the longest part of the large intestine and/or the rectum (the last several inches of the large intestine before the anus).

D

DNA

Molecules within cells that carry genetic information.

G

Gene fusion

A type of gene made by joining parts of 2 different genes. Fusion genes make fusion proteins, which can be the root cause of some kinds of cancer. 

Gynecologic cancers

Cancers found anywhere in the female reproductive tract. This can include the cervix, endometrium, fallopian tubes, ovaries, uterus, and vagina.

L

Long QT syndrome

A condition where the heart beats fast and irregularly. Long QT syndrome might cause a person to faint or have a seizure. In some instances, the heart can beat out of control for so long that it may cause sudden death.

M

Mammary analogue secretory carcinoma

A type of salivary cancer.

N

Neuroendocrine cancers

Cancers that form from cells that release hormones into the blood in response to a signal from the nervous system.

O

Oral

By mouth.

P

Papillary thyroid cancer

The most common type of thyroid cancer.

Protein

A molecule that is needed for your body to function properly. Proteins are the basis of body structures, like skin and hair, and other substances in your body.

S

Salivary cancer

A rare cancer found in the tissues of the gland that makes saliva.

Sarcoma

A cancer that begins in the bone and soft tissue.

Secretory breast cancer

A rare type of breast cancer.

T

Thyroid cancer

Cancer of the thyroid. The thyroid is an organ at the base of the throat. It makes hormones that help control heart rate, blood pressure, body temperature, and weight.

TRK or NTRK

An NTRK gene fusion tells the body to make abnormal versions of TRK, or tropomyosin receptor kinase, fusion proteins. TRK fusion proteins are a family of several proteins that normally plays an important role in the nervous system. People with NTRK fusion-positive solid tumors have an abnormal version of TRK called a TRK fusion protein.